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N achieved by L-NIL administration was entirely lost when mice have been chronically exposed to OVA (Figure 2(b)). Equivalent differential final results have been accomplished applying iNOS-/- mice that have been sensitized and acutely (Supplementary Figure S2A) or chronically (Supplementary Figure S2B) challenged to OVA. The effects of iNOS inhibition on AHR have been related for the differential
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Ucts (AGEs) have been shown to induce AP in human and rat SMCs, respectively [141, 142]. Similarly, 7-ketocholesterol, one of the main oxysterols present in atherosclerotic plaques, triggers in depth vacuolization and intense protein ubiquitination and increases the LC3-II expression in cultured SMCs [143]. SMCs in the brous cap are surrounded by a thick layer of basal lamina and as a result are s
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